Transcript: How do we define the different risk stratification levels in the American Urology Association, the Society of Urologic Oncology, low risk is a small, papillary, non-invasive, lowgrade bladder tumor. It’s a first-time event less than three centimeters in size. The intermediate risk is, typically, the low-risk patients, or the low-grade patients, papillary, non-invasive who have recurred, or they can have multiple low grade papillary tumors, or they can have a large, low grade papillary tumor. In general, they’re all mostly low grade. Now, in the American Urology Association risk stratification, we also include high grade papillary tumors, first time event, less than three centimeters. In general, it’s a solitary tumor, but we can have two to three tumors and still be in the intermediate risk category, especially if they’re small. Anytime a high-grade intermediate risk tumor recurs, they then automatically are in the high-risk category. The highrisk category is essentially anybody with high grade disease, T1, high grade carcinoma in situ, or Ta high grade greater than three centimeters, or recurrent Ta high grade.